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Poster Walks: Poster Walk 8: Interstitial lung disease/ICU/Pediatrics |

P240 Risk of pneumothorax due to air travel in pulmonary lymphangioleiomyomatosis

C. Gonano; J. Pasquier; C. Daccord; R. Lazor
Author and Funding Information

1Medical School, University of Lausanne

2Institute of Social and Preventive Medicine (IUMSP)

3Division of Respiratory Medicine, Lausanne University Hospital, Lausanne, Switzerland


Copyright 2017, American College of Chest Physicians and Swiss Respiratory Society SGP. All Rights Reserved.


Chest. 2017;151(5_S):A140. doi:10.1016/j.chest.2017.04.147
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Extract

Introduction: Pulmonary lymphangioleiomyomatosis (LAM) is a rare disease affecting almost exclusively women and characterized by abnormal proliferation of smooth muscle cells (LAM cells) in the lungs, kidneys and axial lymphatics. In the lungs, LAM cell proliferation lead to the development of multiple thin-walled cysts resulting in the gradual onset of respiratory insufficiency and frequent pneumothorax (PT). Air travel (AT) could further increase the risk of PT in LAM through rupture of subpleural cysts induced by changes in atmospheric pressure in aircraft cabin.

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