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Poster Walks: Poster Walk 8: Interstitial lung disease/ICU/Pediatrics |

P231 Respiratory breathing patterns and cough in idiopathic pulmonary fibrosis: awake, asleep and over time

A. Schertel; M. Funke-Chambour; T. Geiser; A.-K. Brill
Author and Funding Information

Department of Pulmonary Medicine, University Hospital and University of Bern, Bern, Switzerland


Copyright 2017, American College of Chest Physicians and Swiss Respiratory Society SGP. All Rights Reserved.


Chest. 2017;151(5_S):A131. doi:10.1016/j.chest.2017.04.138
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Extract

Background: Idiopathic pulmonary fibrosis (IPF) leads to a restrictive lung defect that has impact on daytime and nocturnal breathing patterns. In this pilot study we assessed the course of day- and nighttime respiration, oxygenation parameters and cough over a period of nine months and differences between wakefulness and sleep in IPF patients.

Methods: 24-hour respiratory polygraphies (RP) (Nox T3, Nox Medical) and pulmonary function tests (PFT) were performed at 1, 2, 4, 8 and 9 months. RPs were manually analyzed and subdivided into periods of assumed wakefulness and sleep. Cough-events were counted manually from the audio-track. Cough-index, oxygenation parameters (SpO2, mean extent of desaturation, desaturation index), respiratory rate and heart rate were assessed for differences between wakefulness and sleep. The first and the last RP were compared to identify changes of these parameters over nine months. Statistical analyses were performed with paired Wilcoxon signed rank tests.

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