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Poster Walks: Poster Walk 3: Sleep/Breathing |

P162 Effect of treatment of central sleep apnoea/cheyne stokes respiration on left ventricular ejection fraction in heart failure - a network meta-analysis.

E.I. Schwarz; S.R. Haile; F. Scherff; M.A. Puhan; M. Kohler
Author and Funding Information

1Department of Pulmonology and Sleep Disorders Centre, University Hospital of Zurich

2Epidemiology, Biostatistics and Prevention Institute, University of Zurich

3Department of Cardiology, University Heart Centre, University Hospital Zurich, Zürich, Switzerland


Copyright 2017, American College of Chest Physicians and Swiss Respiratory Society SGP. All Rights Reserved.


Chest. 2017;151(5_S):A60. doi:10.1016/j.chest.2017.04.064
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Introduction: Heart failure patients with central sleep apnoea/Cheyne Stokes Respiration (CSA/CSR) have a unfavourable prognosis. Both continuous positive airway pressure (CPAP) and assisted servo-ventilation (ASV) are accepted treatment modalities for CSA/CSR. Nocturnal oxygen (O2) is a treatment alternative. Whether treatment of CSA/CSR by these modalities is beneficial for cardiac function is controversial.

Methods: Databases were searched up to November 2016 for randomized controlled trials (RCTs) comparing the effect of any combination of CPAP, ASV, O2 or an inactive control on left ventricular ejection fraction (LVEF) in patients with heart failure and CSA/CSR. A systematic review and network meta-analysis using multivariate random-effects meta-regression was performed.

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