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Poster Walks: Poster Walk 3: Sleep/Breathing |

P161 Obstructive sleep apnoea and quality of life in Fabry disease: a parallel cohort study

T. Gaisl; N. Gerard; N. Sievi; C.F. Clarenbach; P.A. Krayenbühl; M. Kohler; D. Franzen
Author and Funding Information

1Department of Pulmonology, University Hospital Zurich, Zurich

2Department of Internal Medicine, Regional Hospital Linth, Uznach, Switzerland


Copyright 2017, American College of Chest Physicians and Swiss Respiratory Society SGP. All Rights Reserved.


Chest. 2017;151(5_S):A59. doi:10.1016/j.chest.2017.04.063
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Extract

Background. Patients with Fabry disease (FD) often suffer from impaired quality of life and excessive daytime sleepiness. Obstructive sleep apnoea (OSA) is frequently reported among patients with FD, however, its prevalence and its effect on quality of life in this population is unclear.

Methods. Patients with FD recruited from the cohort of the University Hospital Zurich (n=52) were compared in a 1:2-matching adjusted for age, sex, weight and height, with healthy adult controls (n=104). Participants underwent structured interviews (including short-form 36) and level-3 respiratory polygraphy. OSA was defined as apnoea-hypopnoea index ≥5/hour. Logistic regression was used to compare the outcomes.

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