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P160 Agreement between mouth maximal inspiratory pressure and sniff nasal inspiratory pressure in patients with amyotrophic lateral sclerosis and correlation with anthropometric measurements

J.-P. Janssens; D. Adler; R. Iancu Fergolia; A. Poncet; L. Genton Graf; V. Viatte; A.-C. Héritier-Barras
Author and Funding Information

1Department of Medical Specialities

2Department of Clinical Neurosciences

3Department of Health and Community Medicine, Geneva University Hospitals, Geneva, Switzerland


Copyright 2017, American College of Chest Physicians and Swiss Respiratory Society SGP. All Rights Reserved.


Chest. 2017;151(5_S):A58. doi:10.1016/j.chest.2017.04.062
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Introduction: Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease leading to progressive loss of motor function and muscular mass and respiratory failure. Indices commonly used to predict occurrence of respiratory failure include clinical symptoms, daytime arterial blood gases, vital capacity seated and supine, sleep oximetry, and strength of inspiratory muscles assessed by Mouth Maximal Inspiratory Pressure (MIP) and Sniff Nasal Inspiratory Pressure (SNIP). This study aims 1/ to measure agreement between MIP and SNIP in bulbar and non-bulbar ALS patients at diagnosis and 2/ to analyze correlation between MIP, SNIP and anthropometric variables in this population.

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