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P152 Diagnostic discrepancies between rapid and standard polymerase chain reaction laboratory tests for influenza virus detection in nasopharyngeal swabs from symptomatic lung transplant recipients

M.M. Schuurmans; J. Hartwig; P. Hamp; C. Murer; C. Robinson; N.J. Mueller; C. Benden
Author and Funding Information

1Division of Pulmonology

2Division of Infectious Diseases, University Hospital Zurich, Zurich, Switzerland


Copyright 2017, American College of Chest Physicians and Swiss Respiratory Society SGP. All Rights Reserved.


Chest. 2017;151(5_S):A50. doi:10.1016/j.chest.2017.04.053
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Introduction: Lung transplant recipients (LTR) have an increased risk of complications from influenza virus infection. Early treatment with neuraminidase inhibitors is recommended for LTR with suspected influenza virus infection. Standard multiplex polymerase chain reaction (PCR) testing for influenza virus takes 36-48 hours. LTR with suspected influenza are treated empirically with oseltamivir pending the results of the nasopharyngeal swab (NPS). In the influenza season 2016/2017 a rapid test for influenza virus A and B was introduced with PCR-based test results available in 2 hours. The objective of this audit was to compare results obtained with the two different tests in order to detect possible diagnostic discrepancies.

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