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P146 The patients with acute exacerbation of COPD maybe benefit from autotitrating EPAP during noninvasive ventilation: a prospective study

B. Han; S. Zhang; Y. Wang; Y. Song; M. Li
Author and Funding Information

1PLA Rocket General Hospital

2PLA Rocket General Hospital, Beijing, China, Beijing, China


Copyright 2017, American College of Chest Physicians and Swiss Respiratory Society SGP. All Rights Reserved.


Chest. 2017;151(5_S):A43. doi:10.1016/j.chest.2017.04.047
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Introduction To determine whether the patients with acute exacerbation of COPD benefit from noninvasive ventilation, which EPAP is required for a varying range rather than a fixed level.

Methods A randomized,prospective and controlled study, 30 elderly patients in AECOPD were divided into three groups: S/T(spontaneous/time) mode group, AVAPS(average volume assured pressure support) mode group and AVAPS-AE(average volume assured pressure support auto-EPAP) mode group. Each group was accepted noninvasive ventilation therapy (NIV via total face mask), for a period of 48 hours. Parameters in three NIV modes: S/T group(IPAP=18 cmH2O, EPAP =5cmH2O,tidal volume depending on individual BMI); the same adopted in AVAPS mode; AVAPS-AE mode(maximum EPAP=8cmH2O,minimum EPAP=4cmH2O, tidal volume depending on individual BMI) .The arterial blood gas analysis was observed at different time(the 0.5th, 1 st, 2 nd, 24 th and 48 th hour).During the NIV, RR, HR and Borg score were monitored and recorded continuosly. Degree of patients' comfort was measured by the VAS (Visual Analog Scale,0~10).

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    Print ISSN: 0012-3692
    Online ISSN: 1931-3543