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Poster Walks: Poster Walk 1: Airway disease I |

P135 Right heart function and pulmonary pressure in asthma patients during 17 days at high-altitude

P.R. Bader; M. Lichtblau; S. Saxer; S.R. Schneider; P. Appenzeller; M. Furian; B. Estebesova; T. Sooronbaev; K.E. Bloch; S. Ulrich
Author and Funding Information

1Pulmonology, UniversityHospital Zurich, Zürich, Switzerland

2National Center for Cardiology and Internal Medicine, Bishkek, Kyrgyzstan


Copyright 2017, American College of Chest Physicians and Swiss Respiratory Society SGP. All Rights Reserved.


Chest. 2017;151(5_S):A32. doi:10.1016/j.chest.2017.04.035
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Introduction: Asthmatics may benefit from the climate and reduced allergens at altitude. But the hypoxic environment may also be associated with adverse health effects, such as right heart strain due to increased pulmonary artery pressure (PAP), especially during the first days. We studied the right ventricular function (RVF) and SpO2 at lowland, immediately after arrival at 3200m and after 17 days at that altitude in asthmatics.

Methods: Twenty-two asthmatics (living< 800m, means±SD age 44±12y, FEV1 92±19%predicted) who participated in a three-week rehabilitation program at the Tuja Ashu High Altitude Clinic, 3200m, were assessed before departure in Bishkek (Kyrgyzstan, 760m) and on the 2nd and 18th day at 3200m. The RVF was assessed by several echocardiographic indices: tricuspid annular plane systolic excursion (TAPSE), tricuspid annular systolic velocity (TASV), mean (m)PAP, stroke index (SI), and cardiac index (CI). SpO2 was measured by pulse oximetry.

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