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Poster Walks: Poster Walk 1: Airway disease I |

P127 Asthma rehabilitation at high vs. low altitude: randomized controlled parallel-group trial

S. Saxer; S.R. Schneider; P. Appenzeller; P.R. Bader; M. Lichtblau; M. Furian; B. Estebesova; B. Emilov; T. Sooronbaev; K.E. Bloch; S. Ulrich
Author and Funding Information

1Pulmonology, University Hospital Zurich, Zürich, Switzerland

2National Center for Cardiology and Internal Medicine, Bishkek, Kyrgyzstan


Copyright 2017, American College of Chest Physicians and Swiss Respiratory Society SGP. All Rights Reserved.


Chest. 2017;151(5_S):A24. doi:10.1016/j.chest.2017.04.027
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Introduction: Environmental conditions at high altitude reduce allergens and pollution. We thus investigated the additive effect of asthma rehabilitation at high altitude (Tuja Ashu, 3200m, HA) compared to the same rehabilitation at low altitude (Bishkek, 760m, LA) on asthma control.

Methods: For this randomized controlled trial adult asthmatics diagnosed according to Global Initiative for Asthma - guidelines and living in the Bishkek area (< 1000m) were recruited. Patients were randomly assigned to a 3-week in-hospital rehabilitation at either LA or HA, comprising patient education, endurance & strength training, breathing exercises and guided walks (5x/week 30-45min). Co-primary outcomes assessed at 760m were changes in peak expiratory flow (PEF)-variability [(day's highest - day's lowest) / mean of day's highest & lowest], and scores in the Asthma Control Questionnaire (ACQ) from baseline to end-rehabilitation and 3 months thereafter between groups.

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