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Oral Sessions: Session 17: Free Communications - COPD |

107 Which prognostic score to use in clinical COPD practise? An answer merging the assessment of prognostic properties and of clinical applicability

B. Guerra; S. Haile; M.A. Puhan
Author and Funding Information

Epidemiology, Biostatistics and Prevention Institute (EBPI), University of Zurich, Zurich, Switzerland


Copyright 2017, American College of Chest Physicians and Swiss Respiratory Society SGP. All Rights Reserved.


Chest. 2017;151(5_S):A2. doi:10.1016/j.chest.2017.04.003
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Introduction: Many prognostic scores for various diseases and disease outcomes exist. The majority of prognostic scores have never been externally validated. This renders uncertain their accuracy in populations different from the one in which they were developed. Furthermore, the different scores are rarely compared against each other. Thus, practitioners cannot base their decisions on which prognostic score to use on firm evidence.

Methods: Using a novel network meta-analytic technique (Multiple Score Comparison (MSC) meta-analysis), we compared the predictive performance of all the available scores predicting mortality in patients with COPD. We used a large-scale international database of 24 cohorts (15,762 patients with COPD, 1,871 deaths and 42,203 person-years of follow-up).

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