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Correspondence |

Pleurodesis FREE TO VIEW

Vincent Acton, MBBS (Syd)
Author and Funding Information

FINANCIAL/NONFINANCIAL DISCLOSURES: None declared.

Private practice, Sydney, NSW, Australia

CORRESPONDENCE TO: Vincent Acton, MBBS (Syd), 1202/127 Kent St, Millers Point, NSW, Australia 2000


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(6):1424. doi:10.1016/j.chest.2016.09.046
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Published online

In the interesting article in a recent issue of CHEST (September 2016), Marchi and colleagues find that abrasion with local fibrin sealant instillation is as effective as pleurectomy in producing pleurodesis in rabbits.

Perplexingly, pleurodesis (obliteration/ablation of the pleural cavity), which is the presumed objective of the study, was not achieved at all. To claim that different techniques are equally effective when both have just been shown to be equally ineffective seems counterproductive.

This seemingly poor result may not be the fault of the rabbits or the techniques used; perusal of the medical literature fails to identify any other series confirming obliteration/ablation of the pleural cavity following “pleurodesis.”

The answer may well lie in the widely held hypothesis concerning pleurodesis. If, as this evidence shows, pleurodesis does not produce ablation or obliteration of the pleural cavity, then the efficacy of this technique must be due to the well-recognized and reported changes produced in the pleura by the various assaults reducing the permeability of the visceral pleura to air or fluid.

References

Marchi E. .de Carvalho M.V. .Ventureli T.R. .et al Abrasion plus local fibrin sealant produces pleurodesis similar to pleurectomy in rabbits. Chest. 2016;150:661-672 [PubMed]journal. [CrossRef] [PubMed]
 

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References

Marchi E. .de Carvalho M.V. .Ventureli T.R. .et al Abrasion plus local fibrin sealant produces pleurodesis similar to pleurectomy in rabbits. Chest. 2016;150:661-672 [PubMed]journal. [CrossRef] [PubMed]
 
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