RESULTS: Fifty eight patients agreed to participate in the study. 57% were female. Mean age was 53.6 (SD = 15) years. 90% reported graduating from high school.47% reported some college education.40% of respondents reported being employed, 33% retired and 17% disabled. 90%of respondents reported daily EC use. Fifty eight (28%) patients agreed to participate in the study. Of these patients, 57% were female and the mean age was 53.6 (SD 15) years. The majority of patients (90%) reported they had graduated from high school and 47% reported having some college education. Forty percent of respondents reported being employed, 33% retired and 17% disabled. Ninety percent of respondents reported daily EC use. The majority of patients who used EC and had eliminated tobacco smoking, reported decreased shortness of breath and cough. There was a trend toward stronger improvements among ex-smokers (compared to current smokers) for Cough (p=0.11), Shortness of Breath (p=0.11) and Activity Level (p=0.06). Table 1. E-Cigarette Use and Symptoms and Smoking HistoryOverall* (n=58)IncreasedSOB-0 Cough-2 (4%) Activity Level-19 (33%) Decreased SOB-38 (66%) Cough-36 (62%) Activity Level-7 (13%) No Change SOB-19 (33%) Cough-18 (31%) Activity Level-30 (52%) Daily E-Cigarette Users* (n=52)Increased SOB-0 Cough- 1 (2%) Activity Level-18 (35%) Decreased SOB-36 (69%) Cough-33 (63%) Activity Level-6 (11%) No Change SOB-15 (29%) Cough-16 (31%) Activity Level-26 (50%) Currently Smoking Tobacco* (n=19)Increased SOB-0 Cough-1 (5%) Activity Level-3 (16%) Decreased SOB-10 (53%) Cough-9 (47%) Activity Level-4 (21%) No Change SOB-9 (47%) Cough-8 (42%) Activity Level-12 (63%) Ex-Tobacco Smokers* (n=39)Increased SOB-0 Cough-1 (2%) Activity Level-16 (41%) Decreased SOB-29 (74%) Cough-27 (69%) Activity Level-3 (8%) No Change SOB-10 (26%) Cough-10 (26%) Activity Level-18 (46%) *Percent does not add to one hundred because of missing values.