Sleep Disorders: Sleep Disorders 2 |

Gender Differences in Polysomnographic Features of OSA Among African Americans FREE TO VIEW

Edris Meda, MD; Mustafa Mustafa, MD; Mulham Osman, MD; Alem Mehari, MD
Author and Funding Information

Howard University College of Medicine, Washington, DC

Copyright 2016, American College of Chest Physicians. All Rights Reserved.

Chest. 2016;150(4_S):1281A. doi:10.1016/j.chest.2016.08.1395
Text Size: A A A
Published online

SESSION TITLE: Sleep Disorders 2

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM

PURPOSE: Studies from North American clinics have reported that females with obstructive sleep apnea syndrome (OSAS) are about the same age as males but are heavier, have less severe apnea and make up a much smaller proportion of cases. However, there is a scarcity of reports comparing gender differences in polysomnographic findings among African American patients with OSAS.

METHODS: This retrospective study included a cohort of 728 African American patients evaluated for OSAS by overnight polysomnography (PSG) over a period of three consecutive years. Demographic, clinical and PSG findings were analyzed.

RESULTS: The study included a total of 728 African American patients, 480 (65.9%) females and 248 (33.9%) were males. Among these patients, OSA was diagnosed by PSG in 470 (64.6%) patients, 194 (78.2%) in males vs 276 (57.5%) in females (P<0.001). By apnea-hypopnea index (AHI) category, 174 (23.9%) had mild (AHI 5-15/ hr), 108 (14.8%) moderate (AHI>15-30/hr) and 188 (25.8%) had severe OSA (AHI>30/hr). The overall prevalence of obesity (BMI ≥ 30Kg/m2) was 96.6% (mean BMI 41.9± 13.4 Kg/m2). Twenty five (3.4%) patients had normal weight (BMI=20 to 24.9 kg/m2 ), 74(10.2%) over weight ( BMI=25 to 29.9 kg/m2 ), 249 (34.2%) obese (BMI=30 to 39.9 kg/m2 ) and 380 ( 52.2%) morbid obesity( ≥40kg/m2 ). Compared to women, men had a lower mean BMI 36.6±10.3 vs 43.6±14.7 kg/m2; P<0.001 but the mean age distribution was similar (48.9±12.5 vs. 43.6 ±12.9 years; p=0.157) between the genders. The mean AHI during total sleep time was higher in men than in women (36.1±38.2 versus 17.6±29.7events/h, P<0.001). Men also had a significantly lower oxygen nadir, lower mean average oxygen saturation (O2) and a longer time spent with O2 saturation < 88% when compared to women (P for all < 0.001).

CONCLUSIONS: Our study showed African American subjects have a high prevalence of obesity and OSAS. Despite being lighter in weight, African American men were more likely to have a higher AHI, poor sleep quality and suffered more from intermittent hypoxia than women. Further study is needed to explain these differences.

CLINICAL IMPLICATIONS: The burden and consequence of OSAS in African American pts is high and more so in men than women. This implies that further study needs to be done to identify the reason for gender differences in African Americans.

DISCLOSURE: The following authors have nothing to disclose: Edris Meda, Mustafa Mustafa, Mulham Osman, Alem Mehari

No Product/Research Disclosure Information




Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543