Sleep Disorders: Sleep Disorders 2 |

Association of Asthma With OSA: Alternate Overlap Syndrome FREE TO VIEW

Narendra Umashankar, MBBS; K C Agarwal, MD; Gopal Purohit, MD; C R Choudhary, MD; Deepak UG, MD; Isha garg, MBBS; Srikant Agarwal, MBBS
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Dr. S.N. Medical College, Jodhpur, India

Copyright 2016, American College of Chest Physicians. All Rights Reserved.

Chest. 2016;150(4_S):1276A. doi:10.1016/j.chest.2016.08.1390
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SESSION TITLE: Sleep Disorders 2

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM

PURPOSE: To assess the prevalence of OSA in asthmatics and to assess the factors responsible for OSA in asthma

METHODS: 50 patients who met the study criteria were enrolled. Demographic and clinical data including comorbidities were collected. Spirometry was done in all patients and subjected to type 1 polysomnography. Level of asthma control was assessed using GINA 2014 guidelines.

RESULTS: OSA was present in 17 patients (34%). 9 out of 18 females had OSA as compared to 8 out of 32 males. Prevalence of OSA in well, partially and un-controlled asthma was 0%, 17.4% and 68.4% respectively. OSA was significantly associated with increased age (0.001), high BMI (p<0.001), longer duration of illness (p=0.001), exacerbations (p=0.005), high dose inhalational steroids (p<0.001), rhinitis (p=0.04), FEV1% (p=0.001) and poor control of asthma (p<0.001).

CONCLUSIONS: OSA is more common in asthma when compared to general population. Poor control of asthma and disease progression are the important factors that contribute in the development of OSA. Patients having asthma especially poorly controlled asthma may be considered for evaluation for sleep related breathing disorders, if present, could be managed in order to achieve good asthma control.

CLINICAL IMPLICATIONS: Obstructive sleep apnea (OSA) and asthma are common disorders with prevalence of 8% and 2% respectively in India. Both share several risk factors and comorbidities in common. Multiple factors have been postulated for this coexistence, which is referred to as alternate overlap syndrome.

DISCLOSURE: The following authors have nothing to disclose: Narendra Umashankar, K C Agarwal, Gopal Purohit, C R Choudhary, Deepak UG, Isha garg, Srikant Agarwal

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