Carol Davila University of Medicine, Bucharest, Romania
Copyright 2016, American College of Chest Physicians. All Rights Reserved.
SESSION TITLE: Sleep Disorders 1
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM
PURPOSE: Obstructive sleep apnea (OSA) is increasing in prevalence worldwide. The gold standard for diagnosis remains polysomnography which is costly and resource consuming. Nocturnal nasal flowmetry may represent a valuable screening method in a high pretest probability population The aim of this study is to assess the role of nocturnal nasal flowmetry to screen for patients with high pretest probability of OSA.
METHODS: We prospectively evaluated subjects with high pretest probability of OSA (presenting at least three of the following four conditions: daytime sleepiness, snoring, obesity, witnessed apneas). A nocturnal nasal flowmetry (nF) followed by overnight cardiorespiratory poligraphy (PG) was performed in 2 consecutive nights. We analyzed the correlations between Apnea Hypopnea Index (AHI) determined by nF (AHI-nF) and by PG (AHI-PG). Sensibility and specificity of AHI-nF for severe OSA (AHI>30/hour) was also evaluated.
RESULTS: 61 patients were enrolled in the study (43 males), with a median age: 56 (24-75) years, median BMI of 32 kg/m2 (22-50), median AHI-nF: 26.7/hour (2-75) and AHI-PG: 27.7/hour (1.4-76.6). A statistically significant positive correlation (r=0.65, p<0.001) between AHI-nF and AHI-PG was found. The sensitivity and specificity of AHI-nF for severe OSA was 1, respectively 0.62.
CONCLUSIONS: In patients with high pretest probability of OSA, nocturnal nasal flowmetry may represent a valuable screening method.
CLINICAL IMPLICATIONS: Nocturnal nasal flowmetry could be an affordable tool to identify patients with severe OSA.
DISCLOSURE: The following authors have nothing to disclose: Stefan Dumitrache-Rujinski, Dragos Zaharia, Alexandra Sora, Ciprian Gigea, Ionela Erhan, Alexandru Muntean, Alexandru Cocieru, Claudia Toma, Miron Bogdan
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