RESULTS: Out of 209 patients, 39 (18.7%) were high risk, 139 (66.5%) were low risk and 31 (14.8%) were diagnosed cases of OSA. New onset POAF occurred in 96 (45.9%) patients. In the overall population, median age was 67, with 73.2%, 92.8%, and 44.5% were males, whites and obese, respectively. 84.7%, 69.9%, 41.2%, 16.3% and 16.3% had hypertension, coronary artery disease, diabetes, thyroid disorders, and previous history of cardiac surgery, respectively. New onset POAF developed in high vs diagnosed vs low risk for OSA (69.2% vs 41.9% vs 40.3%, p=0.0052). New onset POAF may increases in-hospital mortality (2.1% vs1.8%, p=NS), significantly increases postoperative LOS (8 vs 7 days, p=0.002) and cost ($217810 vs $197527, p=0.024) as compared to no POAF group. Multivariate analysis showed high-risk group had significantly increased risk for new onset POAF as compared to the low-risk group even after adjusting for age, sex, race, smoking status, comorbidities, perioperative variables and previous history and type of cardiac surgery (Odds ratio, 95% CI, 2.6 (1.03, 6.61), p=0.04).