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Signs and Symptoms of Chest Diseases: Student/Resident Case Report Poster - Signs and Symptoms of Chest Disease |

An Unexpected Turn: Hepatopulmonary Syndrome From Breast Cancer-Induced Liver Metastases

Denise Sese, MD; Joseph Khabbaza, MD
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Cleveland Clinic Akron General, Akron, OH


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):1257A. doi:10.1016/j.chest.2016.08.1370
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SESSION TITLE: Student/Resident Case Report Poster - Signs and Symptoms of Chest Disease

SESSION TYPE: Student/Resident Case Report Poster

PRESENTED ON: Tuesday, October 25, 2016 at 01:30 PM - 02:30 PM

INTRODUCTION: Hepatopulmonary Syndrome (HPS) portends worse survival in patients with liver disease presenting with dyspnea. Early confirmation improves 5-year survival rates to 76%, comparable to that of liver transplant patients without HPS1. Diagnosis requires a documented defect in arterial oxygenation (elevated alveolar-arterial gradient) induced by intrapulmonary vascular dilatation 2,3. It is known to occur in different types of liver injury from acute ischemic hepatitis to cirrhosis with or without portal hypertension, and does not correlate with the severity of liver disease.

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