Respiratory Care: Chest Infections |

The Association Between Body Morphotype and Progression of Nontuberculous Mycobacterial Lung Disease: A Prospective Cohort Study FREE TO VIEW

Soo Jung Kim, MD; Soon Ho Yoon; Sun Mi Choi; Jinwoo Lee; Chang-Hoon Lee; Sung Koo Han; Jae-Joon Yim
Author and Funding Information

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, School of Medicine, Ewha Womans University, Seoul, Korea (the Republic of)

Copyright 2016, American College of Chest Physicians. All Rights Reserved.

Chest. 2016;150(4_S):1238A. doi:10.1016/j.chest.2016.08.1350
Text Size: A A A
Published online

SESSION TITLE: Chest Infections

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM

PURPOSE: It has been known that patients with distinctive morphotype were more susceptible to nontuberculous mycobacterial lung disease (NTM-LD). However, there is little data about association between body morphotype and progression of NTM-LD. The objective of the study is to find predictors of progression of NTM-LD focusing on the impact of body morphotype through a prospective cohort study.

METHODS: Data of patients with NTM-LD participated in NTM cohort, started at July, 2011 was analyzed. Inclusion criteria were patients with NTM-LD who fulfilled the 2007 American Thoracic Society/Infectious Diseases Society of America guideline. Progression was defined as requirement of initiation of anti-NTM treatment by clinician based on symptomatic and radiologic aggravation. Body morphotype was measured using the bioelectrical impedance analysis.

RESULTS: Among 150 patients, 47 patients showed progression of NTM-LD during study period. Univariate analysis indicated that the lowest tertile of weight, body mass index, waist and hip circumference, skeletal muscle mass, body fat, body fat percentage or abdominal fat ratio were related to progression of NTM-LD. After adjusting bronchiectasis extent and presence of cavity on chest computed tomography and albumin <3.5g/dL, patients with the lowest tertile of abdominal fat ratio had higher risk to disease progression in comparison with the highest tertile.

CONCLUSIONS: Progression of NTM-LD is associated with body morphotype. Abdominal fat ratio is an independent predictor of progression of NTM-LD.

CLINICAL IMPLICATIONS: Patients with specific body morphotype should be carefully monitored for progression of NTM-LD.

DISCLOSURE: The following authors have nothing to disclose: Soo Jung Kim, Soon Ho Yoon, Sun Mi Choi, Jinwoo Lee, Chang-Hoon Lee, Sung Koo Han, Jae-Joon Yim

No Product/Research Disclosure Information




Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
Infant/toddler pulmonary function tests-2008 revision & update.
American Association for Respiratory Care | 4/3/2009
Removal of the endotracheal tube—2007 revision & update.
American Association for Respiratory Care | 8/17/2007
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543