Pulmonary Vascular Disease: Pulmonary Vascular Disease - PE/DVT |

Residual Vein Thrombosis as Assessed by Computed Tomographic Venography After Pulmonary Embolism FREE TO VIEW

Seung Ick Cha; Sun Ha Choi; Jaehee Lee; Chang-Ho Kim
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Kyungpook National University Hospital, Daegu, Korea (the Republic of)

Copyright 2016, American College of Chest Physicians. All Rights Reserved.

Chest. 2016;150(4_S):1198A. doi:10.1016/j.chest.2016.08.1307
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SESSION TITLE: Pulmonary Vascular Disease - PE/DVT

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM

PURPOSE: The aim of the present study was to investigate predictors for residual vein thrombosis (RVT) in patients with pulmonary embolism (PE), thereby elucidating the clinical significance of RVT on computed tomography (CT) images.

METHODS: PE patients were classified into three cohorts based on the time of indirect CT venography follow-up: within 1 month of the first CT scan, 1-3 months, and 3-9 months. Each cohort was grouped into patients with RVT (RVT group) or without RVT (non-RVT group). Clinical variables between the two groups were compared.

RESULTS: The incidences of RVT were 61% within 1 month, 15% at 1-3 months, and 9% at 3-9 months. Right ventricular (RV) dilation on CT (odds ratio [OR] 8.30, 95% confidence interval [CI] 1.89-36.40, p=0.005) and proximal DVT (OR 6.93, 95% CI 1.90-25.20, p=0.003) were independent predictors for RVT within 1 month, proximal DVT at 1-3 months (OR 6.69, 95% CI 1.53-29.23, p=0.012), and central PE at 3-9 months (OR 4.25, 95% CI 1.22-4.83, p=0.023). RVT was found to be the only significant factor related to the recurrence of venous thromboembolism (VTE) in all patients (OR 4.67, 95% CI 2.24-9.74, p<0.001).

CONCLUSIONS: In most patients, RVT was not detected on CT venography after 3 months. RV dilation on CT, central PE, and proximal DVT could be predictors for RVT, which may subsequently predict VTE recurrence.

CLINICAL IMPLICATIONS: Similar to ultrasonographic residual vein obstruction, RVT on CT may predict VTE recurrence.

DISCLOSURE: The following authors have nothing to disclose: Seung Ick Cha, Sun Ha Choi, Jaehee Lee, Chang-Ho Kim

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