RESULTS: A total of 17 (25%) underwent CDT for treatment of PE. By TTE, 17 patients (25%) had severe RV systolic dysfunction and 20 (30%) had severe RV dilation. McConnell’s sign was present in 43% of subjects. Mean pulmonary artery systolic pressure (PASP) was 43.1. Mean RV basal dilation was 3.9. Mean fractional area of change (FAC) was 25.5. For strain analysis, average GLS was -10.46. Regional strain values were similar. In the CDT subgroup (n = 17) compared to the overall population, mean BNP (745 vs 449, p = 0.07) and PASP (55.67 vs 39.6, p = 0.001) were significantly higher in the pre-treatment thrombolytic group. TAPSE, S’ and fractional area of change were not significantly different. GLS and free wall strain trended worse in the CDT group but also were not statistically different. In the subgroup that received CDT, median time to follow-up TTE was 2.5 days. Following CDT, severe RV systolic dysfunction decreased from 41% to 12%, McConnell’s reporting decreased from 65% to 18% and PASP decreased from 56.4 mmHg to 49 mmHg (p = 0.17). There was no change in GLS (-11.2 vs -11.1) or RV free wall strain (-12.99 vs -13).