METHODS: Subjects included patients and physicians (residents, fellows, and attending physicians) at four teaching hospitals in Indianapolis. We recorded patients’ faces who were undergoing CTPA scanning for suspected PE while the patient watched a standardized visual stimulus. Physicians completed a standardized psychometric assessment of facial affect recognition (Diagnostic Assessment of Nonverbal Accuracy 2-Faces, DANVA) in addition to viewing 73 videos of patients’ faces and answering 2 visual analogue scales (VAS) before and after each video. The sample size of N=50 was estimated to determine a clinically meaningful 10% difference in pretest probability. Disease (CPE+ cardiopulmonary emergencies, including PE, ACS, pneumonia, aortic disasters) was determined by adjudication of outcomes.