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Pulmonary Vascular Disease: Pulmonary Vascular Disease II |

Changes in Intraparenchymal Arterial and Venous Blood Distribution Quantified From CT Scans in Pulmonary Hypertension With Elevated Wedge Pressure

Jasleen Minhas, MD; Farbod Rahaghi, MD; Ramya Radhakrishnan, MD; James Ross, PhD; Aaron Waxman, MD; Raúl San José Estépar, PhD; George Washko, MD
Author and Funding Information

Brigham and Women's Hospital, Medford, MA


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):1179A. doi:10.1016/j.chest.2016.08.1288
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SESSION TITLE: Pulmonary Vascular Disease II

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM

PURPOSE: Group II pulmonary hypertension is arises from increasing post-capillary pressures which may lead to pre-capillary remodeling. Clinical trials using medications developed for group I disease (PAH) have thus far yielded variable results. It has been proposed that this is, in part, due to inability to clearly identify those patients that would benefit from pulmonary vasodilator therapy. Morphologic changes such as pruning and proximal dilation have been described from CT scans and pulmonary angiography of patients with pulmonary hypertension both in PAH as well as group II disease. The differential arterial versus venous presence of these changes has not been previously quantified.

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