RESULTS: Median pulmonary artery systolic pressure was 27mmHg (interquartile range 23-31mmHg) in the study cohort. 149 subjects (5.2%) had PH. Of the 149 subjects with PH, only 4 (2.7%) were also iron deficient; crude PH prevalence ratio 0.5 (95% CI 0.2-1.4) in iron-deficiency. In analysis by quartiles of ferritin, adjusting for age and sex, there was no evidence of association in prevalence ratios for PH in quartiles 2 (PR 1.1, 95% CI 0.7-1.7), 3 (PR 0.8, 95% CI 0.5-1.3), or 4 (PR 0.8, 95% CI 0.5-1.3) compared with quartile 1 (referent group, PR 1). Further analyses of the relationship between pulmonary hypertension and ferritin as a log-transformed continuous variable or by quartiles of serum iron showed a similar lack of evidence for association between pulmonary hypertension and these variables.