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Pulmonary Rehabilitation: Pulmonary Rehabilitation |

Diurnal Mouthpiece Ventilation and Nocturnal Noninvasive Ventilation vs Invasive Mechanical Ventilation in Patients With Amyotrophic Lateral Sclerosis

Antonello Nicolini, MD; Laura Parrinello, RPh; Maura Ferrari-Bravo, MD; Cornelius Barlascini, MD; Paolo Banfi
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Respiratory Diseases Unit, Sestri Levante, Italy


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):1127A. doi:10.1016/j.chest.2016.08.1236
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SESSION TITLE: Pulmonary Rehabilitation

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM

PURPOSE: Amyotrophic lateral sclerosis (ALS) leads to progressive muscular atrophy, muscle weakness in the upper and lower extremities, bulbar palsy, and finally death within 3-5 years due to respiratory failure caused by weakness of the respiratory muscles. Current guidelines recommend noninvasive ventilation (NIV) for symptomatic hypoventilation . Furthermore, several studies have shown that NIV has a positive effect on the quality of life. Inspite of these results, the proportion of ALS patients on tracheostomy invasive ventilation (IMV) is relatively high.

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