Pulmonary Physiology: Pulmonary Physiology |

The Effect of Body Mass Index on Ventilatory Parameters During Exercise FREE TO VIEW

Carissa Monterroso, MD; Lucas Cruz, MD; Debapriya Datta, MD
Author and Funding Information

University of CT Health Center, Farmington, CT

Copyright 2016, American College of Chest Physicians. All Rights Reserved.

Chest. 2016;150(4_S):1114A. doi:10.1016/j.chest.2016.08.1222
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SESSION TITLE: Pulmonary Physiology

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM

PURPOSE: Obesity causes lung restriction and often results in exertional dyspnea. Exercise capacity is reduced in obese subjects, possibly due to impairment in ventilation during exercise. Body Mass Index (BMI) affects exercise capacity (VO2max). Whether BMI affects ventilatory parameters during exercise, thereby contributing to dyspnea has not been studied. The objective of this study was to determine the impact of BMI on ventilatory parameters -maximal voluntary ventilation (MVV), ventilation at maximal exercise (VEmax), Breathing reserve (BR), Respiratory rate (RR) and Tidal volume (VT) at peak exercise during Cardiopulmonary Exercise Testing (CPExT).

METHODS: Patients who underwent CPExT for evaluation of dyspnea in our institution over the last 2 years were studied. The following parameters were obtained from their records: age, gender, BMI, VO2max, MVV, RR, VT, VEmax, and BR during CPExT. Correlation between BMI and respectively MVV, VEmax, RR, VT and BR was determined by using Pearson’s test for linear correlation. p < 0.05 was deemed statistically significant.

RESULTS: Of 84 patients, who underwent CPExT, 58% were females; mean age was 56± 15 years. Mean BMI was: 28.3±5.6 kg/sqm; 33% were obese with BMI > 30. Mean values of studied parameters: VO2 max = 71±5.6 percent predicted (%); MVV = 85 ±23%; VEmax=65±17.6 %; BR = 30±17 percent; RR = 32± 8 breaths/minute; VT = 3±12.4L. The correlation between BMI and respective studied parameters and their statistical significance were as follows: BMI vs. VO2max: r=-0.315, p=0.004; BMI vs. MVV: r = -0.173 , p = 0.14 ; BMI vs. VEmax: r = -0.049 , p = 0.6 ; BMI vs. BR : r = -0.028 , p = 0.80; BMI vs. RR: r = -0.015 , p=0.8 ; BMI vs. VT : r = 0.064, p=0.5.

CONCLUSIONS: BMI has a significant correlation with exercise capacity (VO2max) but does not affect ventilatory parameters.

CLINICAL IMPLICATIONS: BMI does not cause ventilatory limitation to exercise.

DISCLOSURE: The following authors have nothing to disclose: Carissa Monterroso, Lucas Cruz, Debapriya Datta

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