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Procedures: Procedures 2 |

Antiplatelet Therapy in Patients Undergoing EBUS-TBNA: Risk vs Benefit

Kevin Swiatek, DO; Rachel Guthrie, DO; John Elliott, PhD; Kim Jordan, MD
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OhioHealth Riverside Methodist Hospital, Columbus, OH


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):1017A. doi:10.1016/j.chest.2016.08.1123
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SESSION TITLE: Procedures 2

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM

PURPOSE: Endobronchial ultrasound with transbronchial needle aspiration (EBUS-TBNA) has improved the ease with which practitioners can obtain mediastinum tissue samples. However, evidence-based studies are limited regarding best management of dual antiplatelet agents (DAPT) aspirin and clopidogrel, or clopidogrel alone in patients who undergo this procedure. One 2006 study recommended discontinuation of clopidogrel prior to transbronchial biopsy after documenting increased bleeding severity in patients taking clopidogrel. However, a recent retrospective review of 12 patients, suggested that EBUS-TBNA can be performed safely by experienced operators in patients taking clopidogrel. Our study further evaluates adverse bleeding events following EBUS-TBNA in patients exposed to DAPT, clopidogrel only, or aspirin (ASA) alone 5 days prior to the procedure versus patients unexposed to anti-platelet medications.

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