METHODS: We studied all patients who had staging for NSCLC from September 2015 to March 2016 prospectively. Endoscopic staging by combined EBUS-EUS-FNA was performed by a dedicated interventional pulmonology (IP) trained specialist with an assistance of pulmonary fellow. All PET positive lymph nodes, lymph nodes >1 cm including the celiac axis lymph nodes and enlarged adrenal glands were sampled when indicated. At least 2 to 3 different stations were sampled each time and a minimum of 3 passes were made on the particular station being accessed. Stations 2R, 4R, 10 and 11 were sampled through EBUS. Stations 2L, 4L, 7, 8, 9 and accessible structures under the diaphragm were sampled through EUS. The primary outcome measure was the diagnosis of malignancy or abundant lymph node tissue determined by an experienced pathologist.