RESULTS: 185 patients were identified. Median FEV1 was 40% (range 11-50). Median age was 69 (range 37-91), 52% were male, 38% had BDR, 39% had AT, and 15% had EM. Twenty-four (13%) actively smoked and 30 patients died. Patients used a median of 0.25 controllers/month (C/m) (range 0-6). BDR patients used a median 0.33 C/m, and non-BDR patients used 0.16 C/m (p=0.17) . EM patients used 0.23 C/m and non-EM used 0.26 C/m. AT patients used 0.26 C/m and non-AT used 0.20 C/m. None of these differences were statistically significant, although the BDR patients trended towards significance. Patients used 0.7 rescue canisters/month. This figure did not differ between BD, AT and EM subgroups. Over 4 years, patients received a median of 5R canisters, 17 days of ABX and 22 of OCS. Forty-one patients (22%) never purchased a single C and 31 (16%) required no ABX or OCS. Fourteen (7%) patients used 1 or more C/m. Their median age was 65, and median FEV1 was 32%. Eight of these 14 (57%) had AT, 4/14 (29%) has BDR, and 1/14 (7%) had EM. Two (14%) actively smoked. These patients used a median of 19 R, 21 days of ABX and 63 of OCS. These were not different compared to non-compliant patients.