University Hospital Mother Tereza, Tirana, Albania
Copyright 2016, American College of Chest Physicians. All Rights Reserved.
SESSION TITLE: Airways 5
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM
PURPOSE: To determine the severity of emphysema by quantitative measurement of it using automated lung parenchyma analysis software ( %LAV) in COPD patients and correlations of it with forced expiratory volume in the 1 second (FEV1); partial pressure of oxygen (PO2); of carbon dioxide (PCO2) and the ratio between pulmonary artery and aorta diameter PA:A.
METHODS: These is a retrospective cohort study which included 137 patients admitted to hospital for COPD exacerbation during 2014 - 2015. 84.6% were smokers and 8.8% didn't smoke. 50% of the patients were between 55 - 85 years old. For analysis of data SPSS 20, Pearson correlation ( R) and linear regression were used.
RESULTS: There is a good correlation between %LAV and FEV1 with R = - 0.319, p = 0.04. Correlation between %LAV and PA:A with R = - 0.21,p = 0.016. Regression analysis has shown that for 1% LAV increase there is a decrease of % FEV1 by 0.22%. There is a strong correlation between %LAV and airway obstruction and is more evident in the lower right pulmonary lobe.
CONCLUSIONS: Emphysema has a good correlation with the severity of airways obstruction and pulmonary hypertension. Missing of correlation between the severity of emphysema with PO2 and PCO2 can be explained by missing of mismatching between ventilation and perfusion. The changing in compliance of the respiratory system can be the cause of blood gas changes in emphysematous patients.
CLINICAL IMPLICATIONS: %LAV can predict the severity of emphysema and bronchial obstruction
DISCLOSURE: The following authors have nothing to disclose: Perlat Kapisyzi, Eritjan Tashi, Sofiela Telo, Mirela Tabaku, Eugerta Dilka
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