DISCUSSION: Organizing pneumonia is associated with many different exposures and disease processes, and has rarely been associated with lymphoma. There are several case reports of organizing pneumonia in the setting of PPL and chemotherapy, and a few case reports noting organizing pneumonia as the initial presentation of PPL2. PPL-DLBCL is rare and diagnosis can be challenging due to nonspecific presenting symptoms, and often an absence of typical B symptoms. CT imaging is variable, including single or multiple lung nodules, cavitary masses, infiltrates and consolidation. The yield of endobronchial biopsies is only 10-30%3. Diagnosis by video-assisted thorascopic (VATS) or open wedge resection is more accurate, however these are invasive and typically not first line diagnostic modalities. BAL is typically low yield. PPL-DLBCL can be aggressive but is usually responsive to conventional lymphoma chemotherapies. Germinal center phenotype conveys the worst prognosis.