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Lung Cancer: Student/Resident Case Report Poster - Lung Cancer I |

Esthesioneuroblastoma With Widespread Distant Metastasis

Manraj Khosla, MD; Annie Do, MD; Christina Pecci, MD; Taaran Cariappa Ballachanda Subbaiah, MD; Lee Mcghan, MD; Mahesh Seetharam, MD; Richard Sue, MD
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St. Joseph's Hospital and Medical Center, Phoenix, AZ


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):737A. doi:10.1016/j.chest.2016.08.832
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SESSION TITLE: Student/Resident Case Report Poster - Lung Cancer I

SESSION TYPE: Student/Resident Case Report Poster

PRESENTED ON: Tuesday, October 25, 2016 at 01:30 PM - 02:30 PM

INTRODUCTION: Esthesioneuroblastoma (ENB) is a rare, slow growing malignant tumor of neural crest origin comprising less than 5% of sinonasal malignancies. Since 1924, approximately 1400 cases have been reported affecting people mainly in their 2nd and 5-6th decades of life. Classically, the presentation is related to its site of origin and extent of invasion. The most common presenting symptoms are obstructed nasal breathing, rhinorrhea, and epistaxis. Headache and diplopia have also been reported with extension of the tumor into the skull base. ENB’s are thought to arise from the basal layer of olfactory epithelium with reports of ectopic ENB’s located in areas lacking normal olfactory neuro-epithelium. Due to the rarity of this malignancy and its local, slow growing nature, metastatic disease is not recognized as a common presentation.

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