SESSION TITLE: Lung Cancer II
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM
PURPOSE: DNA mismatch repair (MMR) deficiency has recently received increasing attention as a significant biomarker to predict the treatment effect of immune checkpoint inhibitors for various malignant neoplasms. The MMR status can be evaluated by an analysis of microsatellite instability (MSI). The frequency of MSI in non-small cell lung cancers varies considerably in previous reports, ranging from 2-30%. It is difficult to compare these studies because the number of loci analyzed and their locations differ. In the present study, we analyzed MSI for lung adenocarcinomas using the Promega panel, which is the latest and the most reliable diagnostic test for Lynch syndrome.