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Lung Cancer: Lung Cancer I |

The Impact of Preoperative Diffusing Capacity on Prediction of Postoperative Life-Threatening Complications and Long-term Survival in Clinical Stage I Non-small Cell Lung Cancer

Takeshi Mimura, MD; Yoshihiro Miyata, MD; Yuichiro Kai, MD; Masaoki Ito; Tsutani Yasuhiro; Aritochi Hattori, MD; Kazuya Takamochi, MD; Kenji Suzuki, MD; Morihito Okada, MD
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Hiroshima University, Hiroshima, Japan


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):705A. doi:10.1016/j.chest.2016.08.800
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SESSION TITLE: Lung Cancer I

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM

PURPOSE: This study aimed to determine the significance of preoperative diffusing capacity of the lung for carbon monoxide (DLCO) in surgical outcomes in clinical stage I non-small cell lung cancer (NSCLC) patients.

METHODS: We performed a retrospective review of training and validation cohorts that underwent radical resection (R0) for clinical stage I NSCLC between January 2009 and December 2014 at two independent institutions. Each complication was classified according to the Clavien-Dindo classification of surgical complications. Receiver operating characteristic (ROC) curve analysis was performed to identify factors that could predict the incidence of postoperative complications. Several potential prognostic factors were analyzed with respect to outcomes including overall survival (OS).

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