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Lung Cancer: Lung Cancer I |

Diagnostic Value of Micrornas Derived Exosomes From Bronchoalveolar Lavage Fluid in Early Stage Lung Adenocarcinoma

Mi-Hyun Kim, MD; Eun Jung Jo; Jung Seop Eom; Jung Ha Mok; Kwangha Lee; Ki Uk Kim; Hye-Kyung Park; Min Ki Lee
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Pusan National University, School of Medicine, Busan, Korea (the Republic of)


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):703A. doi:10.1016/j.chest.2016.08.798
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SESSION TITLE: Lung Cancer I

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM

PURPOSE: Low-dose computed tomography for lung screening is able to identify smaller nodules more often than can chest radiographs. However, complications of invasive diagnostic procedures of detected nodules are common in practice. Exosomes, membrane vesicles released from cells, contain a diverse array of biomolecules that closely reflect the biologic state of cell and tissue from which they are released. The presence of exosomes in bronchoalveolar lavage (BAL) fluid in various clinical situations has also been reported. However, little is known about the exosomes in BAL fluid in patients with lung cancer, especially early stage lung cancer. We performed this study to investigate diagnostic values in bronchoalveolar lavage (BAL) fluid exosomal micro (mi)RNA in early stage lung adenocarcinoma.

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