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Imaging: Imaging |

Predicting Pericardial Effusions in ESRD: Does PAH Play a Role?

Cameron McBride, BS; Ignacio De Cicco, MD; Vincent Gacad, MD; Patrick Yu, MD; Fiorella Llanos Chea, MD; Ruby Benjamin-Garner, PhD; Gabriel Aisenberg, MD
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University of Texas Health Science Center at Houston Medical School, Houston, TX


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):662A. doi:10.1016/j.chest.2016.08.756
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Extract

SESSION TITLE: Imaging

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM

PURPOSE: Pericardial effusion affects as many as 19% of patients with end-stage renal disease (ESRD)1-6 but the pathophysiology is poorly understood. Incidence declines with more efficient dialysis prescription but it’s unclear whether this is due to metabolite correction or optimization of volume status and hemodynamics7,8. Pericardial effusion has been also associated with pulmonary arterial hypertension (PAH)9-10; Mellins et al.11 indicated the elevated right sided pressures may be a necessary condition for the development and maintenance of pericardial effusion. Yoshida and colleagues demonstrated a more profound predisposition for pericardial effusion in patients with central overhydration than with residual metabolic derangements after dialysis, suggesting that volume status and right heart afterload may be the chief contributors to pericardial effusion in dialysis patients12. The influence of pulmonary hypertension in the origin, persistence and severity of pericardial effusion in ESRD patients has not been addressed in the scientific literature. We aim to assess whether elevated pulmonary arterial pressures measured by non-invasive means predicts the presence and persistence of pericardial effusions in our population of ESRD patients.

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