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Education, Research, and Quality Improvement: Education, Research, and Quality Improvement II |

Lowering of Lactate Threshold for Severe Sepsis Did Not Impact Mortality

Farshid Rafatnia, MD; Ravindra Rajmane, MD
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NYU Lutheran, New York, NY


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):618A. doi:10.1016/j.chest.2016.08.710
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SESSION TITLE: Education, Research, and Quality Improvement II

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM

PURPOSE: In 2015, NYU Lutheran Medical Center, a 450-bed academic teaching hospital sought to reduce mortality from sepsis. In October 2015 the criteria for severe sepsis were modified and the lactate level threshold was decreased from 2.3 mmol/L to 2.0 mmol/L. Furthermore, the diagnosis of sepsis was broadened to include organ dysfunction irrespective of lactate level. Our hospital also identified interdisciplinary teams for intensive education, including simulation training and interactive online modules, to promptly recognize sepsis. Nonetheless, the decreased lactate threshold remained the primary intervention to improve sepsis outcomes. We present a retrospective analysis that demonstrates no significant impact on mortality and and, unexpectedly, worse compliance with the recommended 30ml/kg initial fluids bolus.

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