METHODS: The Cystic Fibrosis CareMessage database can be uniquely modified to create a program targeting a given group or individual participant that the messages will be sent to. The IRB reviewed assent and consent issues. A focus group, consisting of patients with Cystic Fibrosis, their parents and the Pediatric Diagnostic Center's CF team, was used to identify the greatest learning needs of our targeted populations. Patients and their families were consulted in clinic during their CF team visits and of clinic using SurveyMonkey. The CF team was consulted during a post-clinic meeting. The CareMessage programs for COPD and Diabetes were reviewed for messages that crossover into Cystic Fibrosis health. Along with this educational portion of CareMessage, patients will also be sent appointment reminders for visits with the CF team and their Pediatric Pulmonologist, medication refill, daily medication reminders if adherence issues have emerged and the patient has agreed to this intervention, and notices of educational events. Participants are enrolled into the program during their visits with the CF team.