DISCUSSION: Melanomas are fifth most common type of cancer in US, 70% of cases are malignant. Lung metastasis, parenchymal or pleural, occur in about 50% of malignant melanoma. PMM is exceptionally rare. It is paramount to distinguish primary vs metastatic. Diagnostic criteria of primary lung melanoma: no previously removed pigmented skin tumors, no ocular and solitary lung tumor, primary tumor morphology compatible, no melanomas in other organs, and optional autopsy. Pathogenesis is not clearly elucidated. Suggested hypotheses include melanocytes migrating during embryogenesis, cutaneous nevus cells entering dermal lymphatic vessels, or pluripotent stem cells as precursors to melanocytes. Conventional treatment for melanoma is surgery, while chemotherapy, molecularly-targeted and immunotherapy are treatment options for advanced melanoma.