METHODS: This study was a retrospective chart review of patients with bronchopleural fistula. Patient with persistent air leak forty eight hours after insertion of chest tube were analysed in a retrospective review. Some patients based on author's clinical experience were prescribed above mentioned nutritional supplements.Based on review of charts, author was able to identify patients who received: Juven, 1 packet daily, vitamin A 10,000 units once daily, vitamin C 500 mg once daily, folic acid 1 mg once daily, and zinc gluconate 220 mg once daily (Non-Standard Intervention ) versus those who those who did not receive these agents (Standard Intervention ) These two group of patient were compared to each other . The parameter which was monitiored was number of days with chest tube in standard and non standard group. Patient who died from any cause in either group were not included in analysis There were 11 patients in the non-standard intervention group, and 10 patients in the standard intervention group. Descriptive statistics was carried out to determine means, and standard deviations for both groups. Mann Whitney U test (one-tailed, significance level of 0.05) was conducted to determine the level significance for both groups.