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Disorders of the Pleura: Disorders of the Pleura |

High Level of ADA in Pleural Effusion, Diagnostic Value of CEA, NSE, Amylase, Glucose, and Lactic Dehydrogenase for the Differential Diagnosis of Pleural Effusion

Je Hun Kim; Chul Ho Oak; Maan Hong Jung; Tae Won Jang; Hyunseung Je; Jihoon Choi
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Kosin University, Busan, Korea (the Republic of)


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):558A. doi:10.1016/j.chest.2016.08.647
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SESSION TITLE: Disorders of the Pleura

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM

PURPOSE: Increased ADA levels in pleural fluid are reminiscent of tuberculous pleurisy. In practice, values above 40 IU/L in practice present levels of sensitivity and specificity > 90%. But at times, we experience extremly high levels of ADA in pleural effusion not tuberculosis. The difficulty of distingushing tuberculous pleurisy between empyema based on high level of ADA in pleural efffusion has motivated the alternative diagnostic strategy. We have evaluated the diagnostic value of pleural glucose, lactic dehydrogenase (LDH), carcino-embryonic antigen (CEA), neuron-specific enolase (NSE), amylase and each pleural fluid/serum ratio.

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