RESULTS: Out of 352 patients included in the study, 111 (31.5%) were female. Average age (±SD) was 65.7 (4.3).73 (20.7%) patients had no comorbidities, while 113 (32.1%) had one, 96 (27.3%) had two and 70 (19.9%) patients had three or more comorbidities. The univariable Cox-regression analysis indicated that the number of comorbidities is associated with transplant-free survival (HR: 1.09; 95%CI: 1.01, 1.2, p-value=0.034). After adjusting for age, sex, and severity of disease (based on FVC percent predicted value), for each additional comorbidity, risk of mortality increases by 10%. Hence, we categorize the cohort into four groups. Observed mortality was 26%, 24%, 21%, and 13% for patients with none, one, two, and three or more comorbidities, respectively. The major change noted when patients had two or more comorbidities. Furthermore, multivariable analysis showed patients with two or more comorbidities (compared to those with one or none) have 30% higher risk of mortality (HR: 1.29, 95%CI: 1.02, 1.66, p-value=0.035).