CASE PRESENTATION: A 55-year-old male, former smoker, presented to the hospital with left olecranon bursitis complicated by MRSA. He underwent debridement and was placed on i.v. daptomycin and discharged home. On day 7, the patient developed progressive shortness of breath, low grade fevers, and a dry cough. 2 days later, he presented with T=97.6, BP 150/80, HR 112, RR 22, and oxygen saturation 82% on room air consistent with acute hypoxic respiratory failure. He was placed on high flow oxygen and CTA chest demonstrated bilateral, diffuse, patchy ground glass infiltrates with mild bibasilar bronchiectasis and upper lobe paraseptal emphysema. White blood cell count was 17.5 with 4.4% eosinophils (0-5.0%). Daptomycin induced pulmonary toxicity was immediately suspected and was subsequently discontinued. He was transitioned to i.v. vancomycin and cefepime and initiated on high dose i.v. corticosteroids. Bronchoscopy was performed the next day without eosinophilia but with cytology disclosing foamy histiocytes and mixed inflammation. Subsequent cultures disclosed no evidence of microorganisms. He made significant improvement with resolution of peripheral eosinophilia. He was discharged on an 8 week steroid taper with follow up CT chest revealing almost complete resolution of airspace disease.