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Critical Care: Student/Resident Case Report Poster - Critical Care III |

MODS: A Rare Initial Presentation of MCTD

Joshy Pathiparampil, MD; Bradley Schlussel, MD; Francis Christian, MD; Andrew Kessleman, MD; David Ozeri, MD
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SUNY Downstate, Brooklyn, NY


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):419A. doi:10.1016/j.chest.2016.08.432
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SESSION TITLE: Student/Resident Case Report Poster - Critical Care III

SESSION TYPE: Student/Resident Case Report Poster

PRESENTED ON: Tuesday, October 25, 2016 at 01:30 PM - 02:30 PM

INTRODUCTION: Mixed Connective Tissue Disease (MCTD) is described as an overlap of systemic rheumatologic conditions, specifically systemic lupus erythematosus, systemic sclerosis, polymyositis, dermatomyositis and/or rheumatoid arthritis, in combination with high serum titers of anti-U1 small nuclear anti-ribonucleoprotein (anti-RNP) antibodies. The common clinical manifestations of MCTD are Raynaud’s phenomenon, arthralgia, synovitis, esophageal dysfunction, muscle weakness, and swollen fingers; however, serious disease can cause development of pulmonary, renal, cardiovascular, gastrointestinal and central nervous system manifestations.1 We report the first case of multiple organ dysfunction syndrome (MODS) due to mixed connective tissue disease.

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