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Critical Care: Student/Resident Case Report Poster - Critical Care II |

Pulmonary Alveolar Proteinosis: A Cause of Hypoxic Respiratory Failure in a Patient With Acute Myeloid Leukemia

Weijia Wang, MD; Yuanxin Liang, MD; Knarik Arkun, MD
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Tufts Medical Center, Boston, MA


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):406A. doi:10.1016/j.chest.2016.08.419
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SESSION TITLE: Student/Resident Case Report Poster - Critical Care II

SESSION TYPE: Student/Resident Case Report Poster

PRESENTED ON: Tuesday, October 25, 2016 at 01:30 PM - 02:30 PM

INTRODUCTION: Pulmonary alveolar proteinosis (PAP) is a heterogeneous group of congenital and acquired diseases characterized by accumulation of excessive surfactant due to the defect in removal by macrophages. The incidence of secondary PAP in patients with pulmonary symptoms was estimated at about 5% among all the hematologic population, and to 10% in patients with myeloid disorders. With sequential bronchoalveolar lavage (BAL) after a timely diagnosis, reversibility of this disease has been reported. Diagnosis is often only established in autopsy due to clinicians’ lack of vigilance of this disease.

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