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Critical Care: Student/Resident Case Report Poster - Critical Care I |

Baclofen Overdose: Lipid Emulsion; A Lipophilic Antidote

Amee Sodha, MD; Habib Nazir, MD; Mariza De Brito, MD; Marc Lindner, DO; Katherine Chiapaikeo-Poco, DO; Ryan Hill, DO; Jason Manzella, DO; Joshua Lee, MD; Nancy Holder, MD; Nadeem Ali, MD; Pratik Patel, MD; Christina Migliore, MD
Author and Funding Information

Department of Internal Medicine, Newark Beth Israel Medical Center, Newark, NJ


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):375A. doi:10.1016/j.chest.2016.08.388
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SESSION TITLE: Student/Resident Case Report Poster - Critical Care I

SESSION TYPE: Student/Resident Case Report Poster

PRESENTED ON: Tuesday, October 25, 2016 at 01:30 PM - 02:30 PM

INTRODUCTION: Baclofen, a lipophilic GABA agonist, is commonly used in spastic movement disorders like multiple sclerosis(MS). Its use as a muscle relaxant provides symptomatic relief to patients. Adverse effects include hallucinations, hypotension, hypothermia, bradycardia, seizures, coma and death. We present a case of a pt w/ MS who overdosed on baclofen. An unusual therapy historically used in veterinary medicine, intravenous lipid emulsion, was administered after her presentation with favorable results.

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