RESULTS: Among an initial evaluation of 49 patients who screened positive for sepsis at Rush University Medical Center and died during the hospitalization, 29 (59%) met Sepsis-3 criteria. Within three hours of Emergency Room admission, there were 19 (66%) who had blood cultures drawn, 18 (62%) who had broad-spectrum antibiotics started, and 16 (55%) who had lactate measured. Complete adherence to these three measures was more likely to occur in patients with hypotension and/or a lactate ≥4mm/L in the first three hours (OR 9.16, 95% CI 1.49-56, p=0.02). Of the 16 patients with hypotension and/or elevated lactate, 10 (63%) received an appropriate 30 ml/kg crystalloid bolus. There were 9 (31%) who met all of the recommended processes of care within 3 hours of presentation.