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Critical Care: Mechanical Ventilation & Respiratory Failure II |

Efficacy and Safety of Dexmedetomidine in Facilitating Extubation in Mechanically Ventilated Patients

Kevin Dsouza, MD; Mindee Hite, PharmD; Laurie Lerner, MD
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Rochester General Hospital, Rochester, NY


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):321A. doi:10.1016/j.chest.2016.08.334
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SESSION TITLE: Mechanical Ventilation & Respiratory Failure II

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM

PURPOSE: Dexmedetomidine (DEX), a selective alpha-2-adrenergic receptor agonist, possesses sedative, analgesic and anxiolytic properties without causing significant respiratory depression in mechanically ventilated (MV) patients. In MV patients who are difficult to wean off of sedation secondary to agitation, DEX may be able to shorten time to extubation. The purpose of this study is to assess the percentage of MV patients deemed difficult to extubate secondary to agitation that were successfully extubated within 48 hours after initiation of DEX therapy.

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