RESULTS: Severe trauma (n=120), moderate trauma (n=148), mild trauma (n=312), and control group (n=214) were included in the study. Mean Age was 46.8 years (±16.1 SD). Compared to control group, two patterns were evident. One pattern had a longer time to reach the greatest clot growth speed (MaxV-t), a lower speed of maximal clot formation (MaxV) resulting in decreased clot strength (MCF). Severe trauma patients (maxV-t 125 vs. 119s, p=0.002 and MaxV 14 vs. 16 mm/min, p = 0.0001, MCF 62 vs. 63, p=0.01) and patients requiring blood transfusion (MaxV-t 124 vs. 119s, p=0.018 and MaxV 13 vs. 16 mm/min, p = < 0.0001, MCF 62 vs. 63mm, p=< 0.0001) fit in this profile. The other pattern had both longer time to MaxV, and reduced MaxV but no difference in clot strength compared to controls. This profile was present among non-survivors (maxV 14 vs. 16 mm/min, p = 0.015, MaxV-t 133 vs. 119s, p=0.0001, MCF 62 vs. 63 mm, p=0.2).