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Critical Care: Global Case Report Poster - Miscellaneous |

Coexistence of Diffuse Panbronchiolitis and Asthma: Reciprocal Change Between Neutrophilic and Eosinophilic Inflammation

Kiyoshi Takeyama, MD; Yuri Shimizu, MD; Masanobu Ishii, MD; Mami Orimo, MD; Midori Toriyama, MD; Osamitsu Yagi, MD; Etsuko Tagaya, MD; Mitsuko Kondo, MD; Jun Tamaoki, MD
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Tokyo Women's Medical University, Tokyo, Japan


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):270A. doi:10.1016/j.chest.2016.08.283
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SESSION TITLE: Global Case Report Poster - Miscellaneous

SESSION TYPE: Global Case Report Poster

PRESENTED ON: Tuesday, October 25, 2016 at 01:30 PM - 02:30 PM

INTRODUCTION: Diffuse panbronchiolitis (DPB) is a severe idiopathic inflammatory disease that diffusely involves respiratory bronchioles of bilateral lungs. Chronic sinusitis is known to be associated with most of the cases. The airway inflammation is characterized by neutrophils, CD8+ lymphocytes and foamy macrophages, which leads to progressive airflow limitation and bronchiectasis. Because typical symptoms including productive cough, wheezing, shortness of breath and chest tightness are observed both in DPB and asthma, the patients with DPB have often been treated as severe asthma. However, coexistence of these two diseases has not been reported.

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