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Critical Care: Fellow Case Report Poster - Critical Care III |

Nivolumab-Induced Autoimmune Diabetic Ketoacidosis

Ali Zaied, MD; Augustine Lee, MD
Author and Funding Information

Mayo Clinic, Jacksonville, FL


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):255A. doi:10.1016/j.chest.2016.08.268
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SESSION TITLE: Fellow Case Report Poster - Critical Care III

SESSION TYPE: Affiliate Case Report Poster

PRESENTED ON: Tuesday, October 25, 2016 at 01:30 PM - 02:30 PM

INTRODUCTION: Nivolumab, a monoclonal antibody against programmed cell death-1 receptor (PD-1), is increasingly used in advanced cancers. PD-1 is responsible for self-tolerance and prevention of autoimmunity. While PD-1 blockage enhances cancer therapy, it’s associated with immune-related adverse events (AE). We describe an elderly patient who presented in ketoacidosis due to new-onset diabetes mellitus (DM) after receiving nivolumab

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